all natural skin care
since 1972
Dry Aging Skins
Factors that are involved in the aging process that occur in the dermis
Physiological Aging
• The cell renewal rate slows down. Because there is less blood circulation, less oxygen is delivered to skin cells, so they are not replaced as quickly.
• Cell turnover rate slows down so new cells take longer to reach the surface. This leads to a buildup of dull, devitalized, dead surface cells and rough skin texture.
• In the dermis, the synthesis of Elastin and Collagen proteins slows down and a breakdown in these proteins occurs as well. Elastin and Collagen are responsible for the elasticity and strength of the skin. Expression lines deepen and skin begins to sag.
• The barrier lipid region becomes compromised. This barrier layer keeps pollution, chemicals, pathogens, etc, from penetrating and also keeps the lower layers plump with water. The skin becomes more dehydrated and produces less oil as a result.
Biochemical Reactions
• The development of Reactive Oxygen Species - ROS are dangerous oxygen molecules generated by UV rays and pollution. ROS attack and react with stable skin cell molecules, causing cross-linking of collagen and elastin (the cause of wrinkles) while lessening skin’s ability to repair itself.
• The formation of Advanced Glycation End-Products - AGE can contribute to loss of elasticity, wrinkles, inflammation, inhibited skin cell growth and accelerated aging. The same glucose (sugar) that provides energy for our cells can also react with proteins and the skin’s collagen, forming AGEs, a by-product of this glycation reaction.
• The stimulation of Matrix Metalloproteinase enzymes - MMPs are enzymes activated by UV exposure or inflammation. MMPs contribute to the breakdown of collagen while inhibiting new collagen formation.
Because we understand these triggers, as a skin care professional and formulator, our products are better equipped to effectively treat, and control, the signs of skin aging.
Philosophies and Ingredients
* ACell ~ AGEs Aminoguanidine-Blueberry-Carnosine, Copper Peptide, Essential Oils, Fermented Botanical & Sea Extracts, Ferulic Acid, Glucosamine, Glutathione, Glyconutrients, Honey, Quercitin, Resveratrol, Silk, Spin Trap, Stem Cells, Vitamins A B O
* Mer ~ Crème de la Mer ~ Calcium, Iron, Lecithin, Magnesium, Potassium
* Prairie ~ La Prairie ~ Alanine, Algae, Creatine, Cucumber, Glycine, Glycoproteins, Horsetail, Ivy
* Perricone ~ Nicolas Perricone ~ Alpha Lipic Acid, DMAE, Peptides, Polyphenols, Vitamin C ester
* Martyn ~ Tracie Martyn ~ Ceramides, EGF, Glycosaminoglycans, Peptide, SOD
These blends of state of the art peptides and the most powerful anti-oxidants are most ideal for those displaying moderate to severe signs of aging skin. Each Philosophy selected will be added to the product you want customized.
A significant reduction in wrinkle size in just 28 days. An exclusive blend of six powerful, highly concentrated, 100% active wrinkle relaxing and anti-aging peptides are combined with vitamins and skin moisturizers to create this wrinkle fighting solution with the highest degree of effective ingredients found in clinical studies. SS Luminescence helps boost natural collagen production and leaves skin looking soft, smooth and years younger.
BenefitsDeeply hydrates tissues for a healthier skin with proper cell function
Visible results after just one application
Up to a 52% reduction in wrinkle size in just 28 days
Specially formulated to target stubborn areas resistant to other treatments such as laugh lines, brow and forehead furrows
Helps lessen the frequency of wrinkle causing movements for firmer, more resilient skin
Dramatically diminishes the appearance of fine lines and wrinkles for smooth, younger looking skin
Lessens the appearance of deeper, more defined wrinkles
Visibly reduces sagging jowls and turkey neck, giving a more taut appearance to the skin
Brightens skin for a uniform appearance in color and tone
Active Ingredients Argireline at 20% - A peptide cocktail that prevents the formation of lines and wrinkles
Matrixyl 3000 at 25% - Stimulates cells to synthesize their own natural collagen
Hyaluronic Acid at 60% - The best natural moisturizer for skin, restores skin hydration, moisture content, recaptures natural elasticity, prevents wrinkles
CoQ-10 at 3% - More effective than CoQ10 in protecting cells from free radical damage from reduced blood flow, environmental damage, improves the appearance of fine lines, wrinkles, reduces dryness and smooths skin texture
Alpha Lipoic Acid at 7% - Produces nitric oxide which increases healthy blood circulation, shrinks and repairs capillaries, reduces puffiness around the eye, a powerful anti-oxidant that protects skin from free radical damage
Essential Oils - Proprietary blend of anti-aging oils including Red Rose and White Rose with the highest healing vibrations of any essential oil
Jasmine Extract - Stimulates production of natural collagen fibers to reinforce the skin’s supporting foundation, strengthens the skin's self-defense mechanisms, promotes the synthesis of its natural protection systems
EGF - Epidermal Growth Factor is the single most important substance for development and maintenance of both the epidermis and dermis. It is a protein that works to heal and repair the stratum corneum by directly stimulating proliferation of growth factor receptors. EGF has two other bonuses in that it helps "mop up" free radicals, and also has anti-inflammatory benefits. All of the above show why EGF is particularly beneficial to skin that is going through chemical peeling treatments. It helps replace what the peels remove. Using this product in conjunction with peeling makes it much less stressful to the skin by providing fuel for the renewal process.
Beta Glucan - Recent studies with several hundred women, given a cosmetic regimen of which a topical cream containing beta glucan was a major part. The effects on the signs of aging in the skin were evaluated. Compared with the control group, A 27 percent improvement in skin hydration was observed after eight weeks of using the regimen twice a day. An improvement in lines and wrinkles of 47 percent was measured, firmness and elasticity increased by 60 percent, and skin color improved by 26 percent. The rate of skin renewal increased by 34 percent. These dramatic results were achieved because beta glucan rejuvenates the skin's cells by invigorating the macrophages. You can learn more about macrophages by searching in our library. "Specialized" versions of macrophages are found in almost every area of the body, and the skin is no exception, where they are known as "Langerhans" cells, after the scientist who discovered them. These Langerhans cells are found in all parts of the skin, but more so in the upper layers called the epidermis. They're referred to also as dendritic macrophages because dendrites – the spiderweb-like tentacles that emanate out of them – literally permeate throughout the skin, almost like an intricate spiderweb or latticework, and these serve as a source for where the macrophage's receptors can be stimulated. So when you apply a beta lotion or cream topically, it gets exposed to the dendrites of these Langerhans cells, and stimulates or activates them. It's relatively easy from there to understand how supporting immune cells in the skin can lead to healther skin, and enhanced wound healing, but it's less obvious how topical application of beta glucan can reduce the appearance of aging. So let's take a quick look at what happens when we age, and wrinkles and grainy-looking skin appears. First of all, the reason animal cells "stick together" is because of a substance called collagen. It's the "glue" that binds the cells. What happens when we age (and aging can be defined as the sum total of all the insults we receive, from sunlight, chemicals, poor diet, etc.) is that our skin cells die. If our immune system is healthy, these dead cells are “unglued” from the collagen by an enzyme released from the macrophage, called collagenase. Then the phagocytes come in and “gobble up” the debris. This gives room for the new cells to grow in its place. The next step in this process is that epidermal (or "epithelial") growth factors are secreted. These are proteins that act like e-mails or fax messages that are sent out by the macrophages to another type of cell called fibroblasts. The fibroblast comes back to this area where the new cell growth was created and starts to produce collagen again. Without this process, there would be crosslinking of collagen, which creates wrinkles. There would also be granulization on and around dead or damaged tissue, all of which adds up to what we think of as an appearance of aging. The problem, in our modern world, is that so many things tend to destroy, damage or weaken the Langerhans cells. Ultraviolet light from excessive exposure to sunlight, chemicals in soaps and cosmetics, chlorine in the water in which we bathe – these all have a negative effect on the immune cells contained in our skin – and contribute to what we now consider the "normal" appearance of aging. That is why it's extremely difficult to maintain a healthy skin today without giving it a little help. When the immune system, as found in the skin, is functioning properly, the dead and damaged tissue is removed, there is rapid healing, and the result is a smooth repaired area, with good tensile strength. The key to all this, again, is the healthy functioning of the macrophage. And the key to supporting the macrophage is beta glucan. The process by which beta glucan supports overall dermatological health has also been shown to aid wound healing. Several studies have shown dramatic improvements in healing rates (see reference list) with topical application of a salve containing beta glucan. So, once you find a high-quality beta glucan cream or salve, make sure you keep it as a permanent part of your household supplies. For best results, also add it to your sunscreen when venturing outdoors.
Hyaluronic Acid - The Fountain of Youth is pure and concentrated as we use it, a glycosaminoglycan present in the intercellular matrix of skin where it has a conservative, structure balancing and shock-absorbing role. It is currently popular as the ingredient found in the cosmetic injection, Restylane. It naturally occurs in the body, but diminishes as we age or as our bodies become less hydrated. Hyaluronic Acid is the “glue” that binds collagen and elastin in place. It contains amino-polysaccharides called glycosaminoglycans (GAG's), which help increase elasticity and mobility between cells and help the skin repair, renew, and revitalize itself. Hyaluronic Acid is normally found in the joints, the deeper layers of skin, in foetal skin and in the umbilical cord. Medical graded Hyaluronic Acid is usually helpful to diminish the incidence of post-operative adhesions, as a viscoelastic agent in intra-ocular surgery, also as a synovial replacement fluid; and is used to facilitate the healing and regeneration of surgical wounds. The unique properties of Hyaluronic Acid make it the ideal moisturizer. Hyaluronic Acid plays a crucial part in tissue hydration, lubrication and cellular behavior, and has the ability to hold more water than any other biological substance. Its incomparable hydrating properties produce augmented smoothness, softening and decreased wrinkles. Hyaluronic Acid has also proven to give excellent results in the reduction of dryness, itching and burning of the skin. It offers a perfect environment for the reproduction of new cells and healing following skin peels. Hyaluronic Acid is a major component of the extra-cellular matrix that circumscribes quickly dividing cells. It has been demonstrated to be an integral factor in the rapid and scarless wound healing seen in fetal and neonatal tissues. Moreover, the cellular actions precipitated by Hyaluronic Acid are integral to the apparently magical chemical processes of fetal development. It is well documented that fetal tissues have large amounts of Hyaluronic Acid and that decreasing Hyaluronic Acid quantities correlates with aging and wrinkling. Therefore any practical attempts to extend and recapture youth by revivifying damaged tissue should consider the inclusion of this molecule.
Vitamin O - Essential Oils - Nature's Answer To Oxygen Deficiency If there is any one BIG reason for you to use essential oils everyday, it can be summed up in one word...OXYGEN! Essential oils are loaded with it, at least 50 times more oxygen than what the plants give off from which they are derived. While essential oils may contain hundreds of different elements, three primary elements common to all oils are hydrogen, carbon and stabilized OXYGEN. So each time you inhale essential oils or apply them to your body, you are enriching your body with needed oxygen to purge toxins and fight off disease causing pathogens. This is why the use of essential oils on a daily basis can help you develop a superior immune system, and why people who use the oils (several times daily) seldom experience illness and disease. One of the incredible aspects of essential oils is their ability to penetrate and carry nutrients through the cell wall to the cell nucleous. Dr. Radwan Farag, Ph.D., head of the bio- chemistry department at Cairo University, is the man accredited for documenting the oxygenating and antioxidant activity essential oils afford. When the viscosity of blood is reduced, it's velosity increases. By increasing its velosity, our blood is able to deliver greater amounts of oxygen to tissues. When essential oils are introduced to the blood stream, they increase circulation, thereby increasing oxygenation. As the blood delivers nutrients and oxygen to the cells for feeding, it is the oxygenating molecules that penetrate and carry nutrients through the cell wall to the cell nucleous for feeding and oxidation. As the body grows oxygen deficient, individual cells begin to suffer. Without adequate oxygen, cells become nutritionally starved and become a garbage pit for waste and toxins, Deprived of nutrition, the cell protects itself by thickening its outer wall...making nutrient delivery even more difficult. This in turn causes cell deterioration, which can lead to cell mutation. It is in this state that the body becomes a host for disease causing pathogens. Due to their high oxygen content, essential oils are natures most effective catalyst and delivery agent for feeding cells. Rich in oxygen, they pass through the thickest cell walls with the greatest of ease (to maintain or begin a restorative process). This is just one of many ways in which essential oils help us. Because of their vast complexity and human individuality, modern science is just now beginning to realize we have only scratched the surface in understanding how essential oils work and interact within the human body.
White Tea was preceeded by green tea, known for being 200 times more potent than Vitamin E in its ability to destroy free radicals that can cause imperfections and premature aging of the skin. But research points to WHITE TEA -- as being three times more effective an antioxidant than green tea. Independent scientists at Case Western Reserve University in Cleveland have recently found that when a white-tea serum was applied to the skin before sun exposure, the polyphenols in the tea helped protect vital cells from damage during UV over-exposure. Without these, the skin is more prone to premature aging.
EFA-3 contains a unique ratio of Essential Fatty Acid extracts from Ultra-Pure Olive-derived Squalane from Italy along with Emu Oil to match that of the human skin.. Delivering all three Essential Fatty Acids, Omega-3, Omega-6, and Omega-9, directly into thirsty skin for immediate lipid replenishment. Because the body is not able to create Essential Fatty Acids on it’s own, topical supplementation is vital for soft, vibrant, younger-looking skin.
Retinol is the most effective form of vitamin A without a prescription. Retinol has demonstrated to give similar benefits to retin-A but without the irritation (and at a slower pace). Retinol increases cellular turnover which evens out tone and texture and helps skin to function better. Retinol is better than other forms of vitamin A as the molecular structure is smaller.
Anti-microbial Peptides repair disruption of the skin by acne inflammation, infection, sun damage, disease, lesions due to trauma, surgery, burns, accidents, or by chemical, dermabrasion or laser procedures used for skin renewal. AMP generates a signal to the natural immune system and initiates responses that may or may not be effective in a) preventing an impending invasion from surrounding microbes, b) inducing the production of antimicrobial peptides on the surface of the skin, and c) triggering the regeneration of new healthy cells to replace those damaged. Anti-microbial peptides (AMPs) protect the epithelial surfaces of all multicellular organisms from environmental microbes. Collectively AMPs exhibit activity against bacteria, fungi, viruses, and protozoa. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid-rich membranes. Once in a target microbial membrane, the peptide kills target cells through diverse mechanisms. In man the best studied antimicrobial peptides expressed on skin and its appendages are the defensins, the cathelicidin LL37, and the recently described AMP, psoriasin. Most of the known AMPs are inducible. Topical agents such as the glycoconjugates stimulate local expression of epidermal AMPs and represent a novel class of skin care product. Decreased levels of these peptides have been noted for patients with atopic dermatitis and Kostmann's syndrome, a congenital neutropenia. In addition to important antimicrobial properties, growing evidence indicates that AMPs alter the host immune response through receptor-dependent interactions. AMPs have been shown to be important in such diverse functions as angiogenesis, wound healing, and chemotaxis. As our knowledge of AMP biology expands, the precise role and relevance of these peptides will be better elucidated.
Copper Peptides Glycosaminoglycans (GAGs) tightly binds divalent copper cations (Cu 2+) and form copper peptides, with reportedly have skin regeneration properties. The concentration of copper is notable, but copper peptides have been shown to be active in nanomolar amounts. Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing. Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery. The greatest interest in copper peptides is in the area of reversing the effects of human aging and ultraviolet damage on human skin. During aging, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number. A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
Marine Soluble Collagen is collagen that has been processed to enable transdermal delivery. Marine collagen derived from salmon and marine source, naturally contains DMAE. DMAE, made popular by Dr. Nicolas Perricone, is a naturally occurring substance that facilitates the synthesis of a neurotransmitter acetylcholine, which help to maintain skins firmness and facial tone. DMAE also stimulates the synthesis of phosphatidylcholine, an important component of cell membranes. It’s soluble state, being fractionated for transdermal delivery, naturally encapsulates for skin absorption penetrates in the pores of the skin. This provides a significant soluble native collagen inflow, which has the following effects on the skin: It reduces wrinkles, is ultra hydrating, increases tone of the skin, helps healing, supports the growth of cells of the skin, procurez a bright and radiant complexion and it gives an ultra smooth and soft skin.
Emu Oil is derived from the Australian Emu bird, an oil that provides an unparalleled level of natural skin lipids that include omega 3's and essential fatty acids (Lipid-Peptides). Ingredients recommended by the world’s leading dermatologists for youthful skin. Emu Oil is highly moisturizing, a natural skin softener and has rejuvenating properties that have been shown to reduce the depth and length of fine lines and wrinkles. It is also non greasy and highly penetrating to the cellular level. Emu Oil has demonstrated to be the fastest and most penetrating oil into the skin, making it an excellent transdermal carrier for other therapeutic ingredients. It is an effective anti-inflammatory. It is also natural, non-toxic, non-comedogenic (does not clog pores), hypo-allergenic (non-irritating), and gentle for all skin types.
Vitamin K with Haloxyl has amazing anti-aging and anti-inflammatory properties that are wonderful for the eye area and has also been used topically to alleviate the discomfort and irritation following chemical peels and surgery (with the doctor’s permission). Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-3 have great firming and toning properties while the Chrysin, and Hydroxysuccinimide help lessen the under-eye circles and inflammation, and the Theophylline Sillinate is a super active caffeine derivative to draw excess fluid and reduce puffiness. This blend has green tea, cucumber, and chamomile to promote the healing of damaged skin and bruises as wekk as decrease the appearance of: redness of rosacea; dark under-eye circles; spider veins of the face; broken and distended blood vessels; and bruises (must be used two weeks prior to surgery and after surgery).
Vitamin E has been shown to have a wide variety of skin benefits. Many studies have shown that vitamin E can help decrease the effects of psoriasis, erythema, and may help in reducing the risk of skin cancer. Vitamin E has also been shown to significantly help in the reduction of scaring from wounds and has been shown to help reduce the appearance of stretch marks on the skin.
Bioflavonoids or Vitamin P may be active in preserving the structures of capillaries, have an antibacterial effect and promote circulation. They have been shown to aid the effectiveness of other vitamins when used in combination.
Aloe Vera has marvelous medicinal properties. Aloe Vera ‘healing’ comes from Growth Factors, Amino Acids, and minerals such as Zinc, as well as Polysaccharides. These biologically active agents synergize to give us the power of Aloe Vera. Epidermal and Fibroblast growth factors stimulate the Fibroblast directly for growth and repair. The cells as a result migrate within the wound in a proper manner to increase wound healing. Scientists have discovered over 150 nutritional ingredients in Aloe vera. There seems to be no single magic ingredient. They all work together in a synergistic way to create healing and health giving benefits. The ten main areas of chemical constituents of Aloe vera include: Glycoproteins, Gibberellin, Auxin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols. The amino acids in Aloe vera are the building blocks of protein and influence our brain function. Humans require 22 amino acids and the body will make all of them except for eight essential amino acids which our body gets from the food/drinks that we take in. Every one of the essential amino acids are available in Aloe vera and they include isoleucine, leucine, lysine, methionine, phenylalanine, threonine, valine,and tryptophan. Some of the other non-essential amino acids found in Aloe vera include alanine, arginine, asparagine, cysteine, glutamic acid, glycine, histidine, proline, serine, tyrosine, glutamine, and aspartic acid. Located in the sap of the leaves you will find twelve anthraquinones, a phenolic compound that has stimulating effects on the bowels and antibiotic properties. In small amounts the anthraquinones do not have a purgative effect. They help with absorption from the gastro intestinal tract and have anti-microbial and pain killing effects. Too many anthraquinones can produce abdominal pain and diarrhea. The most important anthraquinones are aloin and emodin. They are anti-bacterial, anti-viral, and analgesic. The anthraquinones in Aloe vera breakup residue, pus and lifeless cells, bring blood to the region and flush out material from the wounds and ulcers. Enzymes act as biochemical catalysts that break down the proteins we eat into amino acids. The enzymes turn the food we eat into fuel for every cell in our body, enabling the cells to function and work efficiently. “The main enzymes found in Aloe vera include Amylase (breaks down sugars and starches), Bradykinase (stimulates immune system, analgesic, anti-inflammatory), Catalase (prevents accumulation of water in the body), Cellulase (aids digestion - cellulose), Lipase (aids digestion - fats), Oxidase, Alkaline Phosphatase, Proteolytiase (hydrolyses proteins into their constituent elements), Creatine Phosphokinase (aids metabolism), and Carboxypeptidase.” The next thing we need to ask ourselves is what fuels the enzymes? The key is the vitamins and minerals we take in. For instance if we lack in zinc and/or Vitamin B6, our body will not be able to break down or use protein. Because of the healing properties of Aloe vera and its synergistic action, the body receives what it needs to work properly. Aloe vera, an anti-oxidant rich plant, contains vitamins such as A, C, and E plus the minerals, zinc, and selenium. Anti-oxidants help boost the immune system and combat free radicals in the body. It also contains Vitamins B1, B2, B3, B5, B6, and B12 along with choline, calcium (teeth and bone formation, muscle contractions and heart health), magnesium(strengthens teeth and bones, maintains healthy muscles and nervous system, activates enzymes), zinc (speeds up wound healing, mental quickness assists with healthy teeth, bones, skin, immune system, and digestive aid), manganese (activates enzymes, builds healthy bones, nerves and tissues), chromium (assists with protein metabolism and balancing of blood sugars), selenium which all influence our brain performance. Additional minerals found in Aloe vera include copper (important for red blood cells, skin and hair pigment), iron (involved in oxygen transportation and making of hemoglobin in red blood cells), potassium (helps with fluid balance), phosphorus (helps build bones and teeth, assists with metabolism and body pH), and sodium (regulates body liquids, helps with nerve and muscle performance, and helps deliver nutrients into body cells). Aloe vera also contains the trace minerals of rhodium and iridium used in cancer and tumor research experiments. Another component of Aloe vera consists of the lignins, a major structural material of cellulose content, that allows for penetrative properties. Aloe vera can soak into the skin up to seven layers deep. Lignins penetrate the toughened areas of the skin being beneficial for skin problems such as eczema and psoriasis. The next elements of Aloe vera we will discuss include monosaccharides and polysaccharides. Monosaccharides contain the simple sugars which include glucose. The polysaccharides are the more complex long-chain sugars involving glucose and mannose or the gluco-mannans. These sugars are ingested whole from the stomach. They do not get broken down like other sugars, and appear in the bloodstream in exactly the same form. This process is known as pinocytosis. Once in the blood stream, they exert their healing and immuno-regulating effect. Some of these polysaccharides are not absorbed but stick to certain cells lining the gut and form a barrier preventing absorption of unwanted material so helping to prevent a leaking gut syndrome. The sugars are also used in moisturizing preparations. One polysaccharide, acemannan, is known for its ability to restore and boost the immune system by stimulating the production of macrophages and improving the activity of T-Lymphocytes by up to 50 %. Acemannan produces immune agents such as interferon and interleukin which help to destroy viruses, bacteria, and tumor cells. Acemannan improves cellular metabolism by normalizing cellular function and regulating the flow of nutrients and wastes in and out of the cells. It knows how to destroy parasites and fungus. In some AIDS patients, it even protected the immune system from the toxic side effects of AZT. Carrington Laboratories in the United States have separated the acemannan from Aloe vera. The product is sold as “Carrisyn” and is being used for treatment of AIDS and Feline leukemia. Many sources stated that Aloe vera has mucopolysaccharides, nitrogen containing polysaccharides, found in animals and bacteria. A regulation and testing board for Aloe vera products known as the International Aloe Science Council concludes that some people are misinformed and confused on terminology. The Aloe has polysaccharides but not mucopolysaccharides. Aloe vera contains salicylic acid which is an aspirin-like compound with anti -inflammatory, analgesic, and anti-bacterial properties. It has anti-pyretic properties for reducing fevers. Other constituents of Aloe vera would include prostaglandins, tannins, magnesium lactate, resins, mannins, proteins such as lectins, monosulfonic acid and gibberlin. Another constituent of Aloe vera includes saponins. These are soapy substances from the gel that is capable of cleansing and having antiseptic properties. The saponins perform strongly as anti-microbial against bacteria, viruses, fungi, and yeasts. The plant sterols or phyto-steroids in Aloe vera include Cholesterol, Campesterol, Lupeol, and B (Beta sign) Sitosterol. The plant steroids have fatty acids in them that have antiseptic, analgesic, and anti-inflammatory properties.
Stimulating Collagen Production
According to Dr. Leslie Baumann’s Cosmetic Dermatology, collagen production decreases by approximately 1 percent with each year of age after maturity (about age 21), leading to a loss in firmness and elasticity of skin. So what’s an age-conscious woman to do? Here are some options to stimulating collagen production.
1. Lasers
Two recently developed lasers are the Genesis and Medlite lasers, which have been reported in the Annals of Plastic Surgery to stimulate skin to make new collagen. Genesis and Medlite lasers are only administered by licensed dermatologists. Most women require three to six treatments, and the results should last three to five years. According to the March 2008 issue of Health magazine, Genesis and Medlite laser treatments are about $400 each. Check with a dermatologist near you for pricing and availability.
2. Facial Light Therapy
According to a recent study featured in the March 2008 issue of Allure magazine, LED phototherapy repairs sun damage and increases collagen and elastin production, although “lasers and peels have faster, more substantial results, but more side effects,” according to Seung Yoon Lee, a dermatologist at the National Medical Center in South Korea. With regards to LED therapy’s fewer side effects, Lee adds, “LED is safe for dark skin, unlike some lasers.”
According to Allure magazine, in the study, the researchers treated one side of 61 subjects’ faces with a light-emitting diode machine, while 15 others received a one-sided placebo treatment. Twelve weeks later, only the LED-targeted skin had a decrease in wrinkles (26-36 percent) and an increase in elasticity (14-19 percent). LED therapy seems to increase collagen and elastin production, although less significantly than lasers and peels.
3. Retinoid Treatments According to research by Fisher et. al cited by Dr. Baumann in Cosmetic Dermatology, retinoids are effective in preventing and treating the collagen loss caused by photodamage. UV exposure decreases collagen type I and collagen type III with 24 hours, but treatment of the skin with all-trans retinoic acid prevents the loss of these types of collagen synthesis. In addition, Fisher et. al demonstrated that application of tretinoin inhibits the induction of matrix metalloproteinase genes, which are in part responsible for collagen degradation. Your best option is to talk to your dermatologist about prescription retinoid treatments.
4. Glycolic Acid Peels
According to a 1998 study in Dermatological Surgery, glycolic acid treatments increase fibroblasts’ production of collagen in vivo (in hairless mice) and in vitro (in human skin fibroblast culture) better than either lactic acid or malic acid. However, if you’re deciding between prescription-strength retinoids and over-the-counter glycolic acid peels, you may want to choose the prescription retinoid cream. According to a randomized, placebo-controlled double-blind study, it was found that 0.05% all-trans-retinoic acid was more effective than 10% glycolic acid (a concentration found in at-home treatments) in treating signs of aging.
5. Topical Ascorbyl Palmitate Vitamin C Treatments
According to a review in the International Journal of Pharmaceutics, vitamin C triggers collagen production and thereby increasing skin firmness. Dr. Jeannette Graf also adds in Dr. Burgess’s Cosmetic Dermatology text, “Topical vitamin C increases levels of tissue inhibitors of collagen-degrading matrix metalloproteinases (MMP-1).” Vitamin C is particularly potent in conjunction with vitamin E; unfortunately, a 2008 Dermatology Therapy study cited in Best Life magazine found that very few products containing these vitamins remain effective. This is most likely because vitamin C becomes esterified and inactive upon exposure to light, air, and heat. Your best bet? Keep your vitamin C and E product tightly sealed and in a cool, dark place, or consider a stabilized form of vitamin C, although less research has been done on the effects of, say, 2% ascorbyl palmitate than 15% L-ascorbic acid.
6. Topical Peptide Treatments
Palmitoyl pentapeptide-3 has been shown to stimulate feedback regulation of new collagen synthesis and to result in an increased production of extracellular matrix proteins (collagen types I and II and fibronectin). For these reasons, palmitoyl pentapeptide-3 is increasingly popular in skin care products.
Palmitoyl oligopeptide is a second sequence of collagen-stimulating peptides. A 2007 study in Dermatologic Therapy suggests that palmitoyl oligopeptide significantly stimulates human skin collagen production in fibroblasts, which may slow the degradation of collagen over time.
7. Treatments with Collagen in the Ingredients
Collagen in skin care products acts as only a superior moisturizing ingredient. Topically applying collagen has never been shown to stimulate collagen synthesis or growth. This is because, according to Dr. Leslie Baumann in Cosmetic Dermatology, topically applied collagen is too large to fit through the stratum corneum (uppermost layer of the skin), as collagens have a molecular weight of 15000 to 50000 daltons, whereas only molecules of molecular weight 5000 or less can typically penetrate the skin.
8. Prevent Future Collagen Loss!
Don’t smoke. Wear sunscreen everyday and limit UV exposure. Eat - and topically apply - lots of anti-oxidants, which has been shown to be more effective than either method alone. Use retinoids or alpha hydroxy acids to increase cell turnover. And exercise - although the link between exercise and skin’s collagen production is only implied, always remember, what’s good for your health is good for your skin.
If you're like most people, you probably understand that collagen loss leads to aging skin and for that reason you need to use our skin care serum that contains collagen stimulating actives in order to combat its loss. It's important to understand that rubbing collagen into your skin is not going to prevent its loss. In order to combat the loss of collagen, you need to learn how to naturally produce collagen by using products that contain certain active ingredients. It might sound like a difficult task to naturally produce collagen protein. However, it is actually quite simple. A select few ingredients are known to stop the loss of collagen and elastin and stimulate their re-growth naturally. Here are the active ingredients that your skin needs in order to combat collagen loss.
1. Keratin
Hands down the best ingredient available for stimulating the collagen production in your skin. Keratin is a protein found throughout the body, which has an important structural role in the skin. The ability to convert natural keratin into a functional form that is readily-available to the skin is a recent breakthrough. This is a new exciting, cutting edge substance. Bioactive Keratin actually stimulates your own collagen to grow again. In fact, it is proven in clinical trials to stimulate not only the regrowth of collagen but also elastin, thereby promoting firmness and elasticity. In short, fewer wrinkles, and more youthful, healthier looking skin. It may help improve your skin's ability to retain its needed natural moisture.
Indeed, studies show a sustained 14% improvement in skin moisture retention over 18 days. Studies also show a sustained improvement in skin elasticity of 42% over 18 days. Bioactive Keratin penetrates your skin deeply and creates an invisible barrier that protects your skin and locks moisture in, which scientific studies show stimulates the production of new skin cells. Keratin stops the loss of collagen and stimulates its production. It also stimulates the production of elastin, another vital protein in the skin.
2. Active Manuka Honey
A special honey from New Zealand has unique healing properties. It has been used in skin care for centuries by the Maori people of New Zealand and it's easy to understand why. When used topically, Active Manuka Honey can restore and rejuvenate your skin. It supports the skin cell renewal process and assists in the formation of stronger collagen protein. As an added benefit, active manuka honey is rich in antioxidants and helps to reduce blemishes.
3. Avocado Oil If you want to know how to naturally produce collagen, you need to use face masks or creams that contain avocado oil. Avocado oil is deeply hydrating and highly compatible with the natural oils in your skin. Avocado oil is high in plant steroids, which help to reduce blemishes and age spots. It also helps to regenerate and rejuvenate skin damaged by free radicals. Avocado oil is important because it is scientifically proven to stimulate collagen production and it increases the proportion of soluble collagen in the dermis of your skin.
4. Wakame Sea Kelp
Wakame sea kelp extract is an exotic kelp native to the Japanese Sea, which raises the levels of hyaluronic acid in your skin by stopping the enzyme that is breaking it down. This increase will act to greatly smooth out many of the lines on your face. It works by blocking a harmful enzyme in your body called hyaluronidase. Hyaluronidase breaks down hyaluronic acid in your skin. You may think "well who cares." Well, you should because without hyaluronic acid, the elastin and collagen fibers lose their "glue," which leads to a loss of youthful appearance and dark eye circles. If you research this on Wikipedia, you will read, for example, "Hyaluronan is also a major component of skin, where it is involved in tissue repair."
5. CoEnzyme Q-10, Idebenone, Ubiquinone
In the 1970s and 1980s, researchers had been studying the potential of Coenzyme Q10 (CoQ10) to reduce free radical damage. A vitamin-like natural compound found in all aerobic organisms, it plays an important role in cellular energy production and is also an effective antioxidant. Trying to boost CoQ10's therapeutic effects, scientists synthesized and tested a variety of its chemical analogs and derivatives. Most of these derivatives were found ineffective or unsafe. However, one of the few exceptions was idebenone. It is closely related to CoQ10 in its structure. However, Idebenone is more effective than CoQ10 in protecting cells from the free radical damage resulting from reduced blood flow. The benefits of this ingredient include shielding skin from environmental damage, improving the appearance of fine lines and wrinkles, and reducing dryness and smoothing skin texture. If you look at the ingredient list for some of the better skin care products, you'll often see CoQ10 listed. CoQ10 is short for Coenzyme Q10, so you may also see it listed this way. CoQ10 is a vitamin like substance that is found in all of our body's cells and is very important for healthy skin. CoQ10 is a powerful anti-oxidant. A lot of skin damage and aging comes from free radicals wreaking havoc in our body's cells. CoQ10's anti-oxidant ability can counter these free radicals before damage occurs. Unfortunately, like many other vital substances, as we age, the amount of CoQ10 in our bodies becomes depleted. CoQ10 can penetrate deeply, it is extremely effective at ‘gobbling up’ free radicals in your skin. The result is a powerful anti-wrinkle effect, and can also promote collagen and elastin production as well. Together, these main active ingredients are some of the most powerful anti-aging skin care compounds available, and can significantly improve the look and feel of your skin. As you can see, it is possible to stop the loss of collagen protein in your skin, you can stimulate its re-growth. The result will be more youthful skin with improved elasticity, firmness, and tone. You will also notice a dramatic reduction in wrinkles and fine lines. Within days of using this serum, you will see a dramatic difference in the way your skin looks and feels by learning how to naturally produce collagen. So toss those "collagen" creams out and start using our CP Serum for a skin care product that will actually help you re-grow the collagen you have lost!
Idebenone is a Superceutical for The Next Level of Skin Rejuvenation and Free Radical Protection
What is it? Idebenone is the bioengineered cousin of the vital human antioxidant enzyme - CoEnzyme Q10 - but its 60% smaller (so it penetrates the skin) and up to 1000x more effective, simply put its "Super CoQ10".
How does it work? It targets aging at the cellular source - the mitochondria where it helps to revitalize the skin's cells by eliminating excess free radical formation that results from the way cells make energy - in effect it corrects the essence of cellular aging.
How is it unique? Unlike vitamin and botanical antioxidants, Idebenone is a respiratory chain antioxidant, a totally new kind of antioxidant, which can correct the signs of aging and also offers the highest protection against harmful environmental free radical stress with an Environmental Protection Factor of EPF 95, the highest rating of all antioxidants tested.
Why should I use it? Idebenone delivers a whole new level of skin rejuvenation that you cannot get from AHA, Vitamin A, Vitamin C or other cosmeceuticals because of its absolutely unique mode of action. If you have reached a plateau with your current skin care regimen and want the highest level of skin rejuvenation you can only get this from Idebenone the Superceutical.
Idebenone delivers multiple anti-aging benefits: • Helps prevent skin aging at its cellular source • Decreases the appearance of fine lines and wrinkles • Improves uneven skin tone and texture • Brightens the look of skin • Reduces the appearance of unwanted pigmentation • Offers maximum protection against environmental stress – EPF 95
6. Alpha Lipoic Acid
Lipoic acid is the strongest and longest lasting antioxidant. Lipoic Acid is both water-soluble and oil-soluble. Extremely powerful antioxidant that helps Vitamins C and E work more effectively in the skin. 400 times more powerful than Vitamin C as an antioxidant. Increases gluathione, the body's most important antioxidant. Powerful anti-inflammatory. It has anti-inflammatory qualities, which can be helpful in reducing the redness associated with rosacea, acne and sensitive skin types. It reduces the appearance of wrinkles, fine lines, dull skin, puffy eyes, and dark circles. This means it can fight free radicals in any part of a cell (intracellular) as well as the spaces in between the cells (intercellular). Lipoic acid increases the cell's metabolism, which allows the cell to take in more nutrients, eliminate more wastes, and replace more damaged components. It increases the free radical fighting properties of other antioxidants. Lipoic acid activates the transcription factor AP-1 that produces collagen-digesting enzymes that digest damaged collagen. Damaged collagen is responsible for wrinkles and scars so eliminating the damaged collagen can reverse aging. Lipoic acid is credited with reducing under-eye puffiness, sallow skin, enlarged pores, redness, lines, wrinkles, and acne scars.
Pepha-Tight
Pepha-Tight is a highly purified biotechnologically produced extract from the microalgae Nannochloropsis oculata combined with a well balanced fraction of polysaccharides. Pepha-Tight functions as a skin tightener which provides immediate tightening to the skin. It has been shown to protect human fibroblasts from oxidative stress, simultaneously increasing the formation of collagen-l thereby promoting a long term tightening effect through the strengthening of the skin's connective tissue. Pepha-Tight can be used for all skin tightening applications including lifting products, masks, decollete treatments, gels and serums.
Syn-Ake Tripeptide
Syn-Ake is formed from three amino acids joined by a peptide bond which forms the protein, or the synthetic version, of Viper venom. Syn®-ake has been developed as efficient smoothing and anti-wrinkle care particularly effective for expression lines by relaxing facial muscles. Addresses expression line, expression lines, fine lines, wrinkles, frown lines, worry lines, crows feet, laugh lines, pucker lines. The active compound derived from Heather Extract inhibits the action of the elastase enzyme which degrades the skins matrix. Documented claims shows that the formulation has the ability to reduce forehead expression line wrinkles by 52 per cent and crow's feet by 38 per cent in under one month.
Tripeptide mimics the activity of Waglerin 1, a protein found in the venom of the Temple Viper, Tropidolaemus wagleri 5% – a synthetic Tripeptide with excellent expression line anti-wrinkle properties. The peptide mimics the neuromuscular blocking properties of Waglerin 1, a polypeptide found in the venom of the snake Tropidolaemus wagleri. Reduce the appearance of wrinkles by 22% the 1st week. Tripeptide 5% Complex is the most effective alternative. This simple molecule, discovered in snake venom, has the effect of blocking neural signaling and muscular contraction.
Viper Serum is a natural and powerful alternative to BOTOX® and other cosmetic procedures, melting wrinkles and dramatically reducing fine lines within 20 minutes of application, and has a lasting effect. This reverses the signs of aging and can be used on the forehead, eye area, crow's feet, cheeks, laugh lines, lip area, and stretch marks on the body. In clinical studies, 100% of the respondents experienced a 50-90% reduction in the visible appearance of fine lines and wrinkles within 10 minutes of application. Our serum combines the tripeptide protein with a number of peptides and focused derivatives, including Antarticine, APT, MDI Complex, Aldenine, Pepha Tight, EUK 134 (an anti-oxidant) and a Hyaluronic Acid. Tripeptide mimics the activity of Waglerin 1, a protein found in the venom of the Temple Viper, Tropidolaemus wagleri 5% – a synthetic Tripeptide with excellent anti-wrinkle properties. The peptide mimics the neuromuscular blocking properties of Waglerin 1, a polypeptide found in the venom of the snake Tropidolaemus wagleri. Reduce the appearance of wrinkles by 22% the 1st week. Tripeptide 5% Complex is the most effective alternative. This simple molecule, discovered in snake venom, has the effect of blocking neural signaling and muscular contraction. Similarly, Botulinum Toxin (Active ingredient in BOTOX®) has the same mode of action when injected subcutaneously. Tripeptide is a smaller molecule than Botulinum Toxin, and is able to traverse the skin barrier effectively. The effects are unsurpassed when compared with any product on the market.
This high quality serum contains the best ingredient technology available in the market. This new active ingredient is safe, extensively tested, and approved for use in cosmetics. Why endure injections and costly medical procedures! Tripeptide is a revolutionary new compound discovered in snake venom, which relaxes facial muscle contractions. It works in exactly the same way that Botox Injections work. The difference is that Tripeptide works as a topical alternative, instead of injection. As well, it is reversible when usage is discontinued. There is no other product on the market, which is as efficacious. The discovery of this new Tripeptide enables consumers to have a Botox cosmetic alternative. Peptides are protein fragments. Tripeptide is a series of amino acids in sequence, which has bioactive response on muscular contractions. Viper Serum is a natural and powerful alternative to BOTOX® and other cosmetic procedures, melting wrinkles and dramatically reducing fine lines within 20 minutes of application, and has a lasting but not permanent effect. This reverses the signs of aging and can be used on the forehead, eye area, crow's feet, cheeks, laugh lines, lip area, and stretch marks on the body. In clinical studies, 100% of the respondents experienced a 50-90% reduction in the visible appearance of fine lines and wrinkles within 10 minutes of application.
Collagen and Collagen Synthesis
Many ingredients claim to help you naturally produce more collagen, but D (SS) Serum actually contains REAL ingredients that naturally stimulate the collagen production in your skin. It is very hard to find a product that contains all these collagen boosters because it is complex to properly manufacture, takes much longer to and is expensive to produce. The most powerful substance to help keep skin stay young, soft and vibrant is collagen. Collagen is what gives young skin its firmness. It is a natural protein that provides our skin with structural support. By replenishing the collagen levels in our skin, the aging process is drastically slowed down and existing wrinkles are quickly reversed or repaired. Collalgen helps skin become thicker, more youthful and elastic with hydrated skin so you begin looking younger within the first week. Fine lines and wrinkles begin to disappear and deeper wrinkles recede within three weeks, the face actually undergoes a visible change of youthful contour. Collagen is the glue that holds the body together. Collagen is the most abundant structural protein in the body 60% of the body is made up of connective tissue and collagen represents 80% of all connective tissue. 75% of the dermis consists of collagen and it accounts for 90% of dermal volume. From the age of approximately 25-35 years onwards the body loses collagen at a rate of 1.5% per annum. Collagen is not available from food. There are many face-lift programs and treatments on the market. But, these mostly work on the surface of the skin.
• The development of Reactive Oxygen Species - ROS are dangerous oxygen molecules generated by UV rays and pollution. ROS attack and react with stable skin cell molecules, causing cross-linking of collagen and elastin (the cause of wrinkles) while lessening skin’s ability to repair itself.
• The formation of Advanced Glycation End-Products - AGE can contribute to loss of elasticity, wrinkles, inflammation, inhibited skin cell growth and accelerated aging. The same glucose (sugar) that provides energy for our cells can also react with proteins and the skin’s collagen, forming AGEs, a by-product of this glycation reaction.
• The stimulation of Matrix Metalloproteinase enzymes - MMPs are enzymes activated by UV exposure or inflammation. MMPs contribute to the breakdown of collagen while inhibiting new collagen formation.
Because we understand these triggers, as a skin care professional and formulator, our products are better equipped to effectively treat, and control, the signs of skin aging.
Philosophies and Ingredients
* ACell ~ AGEs Aminoguanidine-Blueberry-Carnosine, Copper Peptide, Essential Oils, Fermented Botanical & Sea Extracts, Ferulic Acid, Glucosamine, Glutathione, Glyconutrients, Honey, Quercitin, Resveratrol, Silk, Spin Trap, Stem Cells, Vitamins A B O
* Mer ~ Crème de la Mer ~ Calcium, Iron, Lecithin, Magnesium, Potassium
* Prairie ~ La Prairie ~ Alanine, Algae, Creatine, Cucumber, Glycine, Glycoproteins, Horsetail, Ivy
* Perricone ~ Nicolas Perricone ~ Alpha Lipic Acid, DMAE, Peptides, Polyphenols, Vitamin C ester
* Martyn ~ Tracie Martyn ~ Ceramides, EGF, Glycosaminoglycans, Peptide, SOD
These blends of state of the art peptides and the most powerful anti-oxidants are most ideal for those displaying moderate to severe signs of aging skin. Each Philosophy selected will be added to the product you want customized.
A significant reduction in wrinkle size in just 28 days. An exclusive blend of six powerful, highly concentrated, 100% active wrinkle relaxing and anti-aging peptides are combined with vitamins and skin moisturizers to create this wrinkle fighting solution with the highest degree of effective ingredients found in clinical studies. SS Luminescence helps boost natural collagen production and leaves skin looking soft, smooth and years younger.
Benefits
Active Ingredients
EGF - Epidermal Growth Factor is the single most important substance for development and maintenance of both the epidermis and dermis. It is a protein that works to heal and repair the stratum corneum by directly stimulating proliferation of growth factor receptors. EGF has two other bonuses in that it helps "mop up" free radicals, and also has anti-inflammatory benefits. All of the above show why EGF is particularly beneficial to skin that is going through chemical peeling treatments. It helps replace what the peels remove. Using this product in conjunction with peeling makes it much less stressful to the skin by providing fuel for the renewal process.
Beta Glucan - Recent studies with several hundred women, given a cosmetic regimen of which a topical cream containing beta glucan was a major part. The effects on the signs of aging in the skin were evaluated. Compared with the control group, A 27 percent improvement in skin hydration was observed after eight weeks of using the regimen twice a day. An improvement in lines and wrinkles of 47 percent was measured, firmness and elasticity increased by 60 percent, and skin color improved by 26 percent. The rate of skin renewal increased by 34 percent. These dramatic results were achieved because beta glucan rejuvenates the skin's cells by invigorating the macrophages. You can learn more about macrophages by searching in our library. "Specialized" versions of macrophages are found in almost every area of the body, and the skin is no exception, where they are known as "Langerhans" cells, after the scientist who discovered them. These Langerhans cells are found in all parts of the skin, but more so in the upper layers called the epidermis. They're referred to also as dendritic macrophages because dendrites – the spiderweb-like tentacles that emanate out of them – literally permeate throughout the skin, almost like an intricate spiderweb or latticework, and these serve as a source for where the macrophage's receptors can be stimulated. So when you apply a beta lotion or cream topically, it gets exposed to the dendrites of these Langerhans cells, and stimulates or activates them. It's relatively easy from there to understand how supporting immune cells in the skin can lead to healther skin, and enhanced wound healing, but it's less obvious how topical application of beta glucan can reduce the appearance of aging. So let's take a quick look at what happens when we age, and wrinkles and grainy-looking skin appears. First of all, the reason animal cells "stick together" is because of a substance called collagen. It's the "glue" that binds the cells. What happens when we age (and aging can be defined as the sum total of all the insults we receive, from sunlight, chemicals, poor diet, etc.) is that our skin cells die. If our immune system is healthy, these dead cells are “unglued” from the collagen by an enzyme released from the macrophage, called collagenase. Then the phagocytes come in and “gobble up” the debris. This gives room for the new cells to grow in its place. The next step in this process is that epidermal (or "epithelial") growth factors are secreted. These are proteins that act like e-mails or fax messages that are sent out by the macrophages to another type of cell called fibroblasts. The fibroblast comes back to this area where the new cell growth was created and starts to produce collagen again. Without this process, there would be crosslinking of collagen, which creates wrinkles. There would also be granulization on and around dead or damaged tissue, all of which adds up to what we think of as an appearance of aging. The problem, in our modern world, is that so many things tend to destroy, damage or weaken the Langerhans cells. Ultraviolet light from excessive exposure to sunlight, chemicals in soaps and cosmetics, chlorine in the water in which we bathe – these all have a negative effect on the immune cells contained in our skin – and contribute to what we now consider the "normal" appearance of aging. That is why it's extremely difficult to maintain a healthy skin today without giving it a little help. When the immune system, as found in the skin, is functioning properly, the dead and damaged tissue is removed, there is rapid healing, and the result is a smooth repaired area, with good tensile strength. The key to all this, again, is the healthy functioning of the macrophage. And the key to supporting the macrophage is beta glucan. The process by which beta glucan supports overall dermatological health has also been shown to aid wound healing. Several studies have shown dramatic improvements in healing rates (see reference list) with topical application of a salve containing beta glucan. So, once you find a high-quality beta glucan cream or salve, make sure you keep it as a permanent part of your household supplies. For best results, also add it to your sunscreen when venturing outdoors.
Hyaluronic Acid - The Fountain of Youth is pure and concentrated as we use it, a glycosaminoglycan present in the intercellular matrix of skin where it has a conservative, structure balancing and shock-absorbing role. It is currently popular as the ingredient found in the cosmetic injection, Restylane. It naturally occurs in the body, but diminishes as we age or as our bodies become less hydrated. Hyaluronic Acid is the “glue” that binds collagen and elastin in place. It contains amino-polysaccharides called glycosaminoglycans (GAG's), which help increase elasticity and mobility between cells and help the skin repair, renew, and revitalize itself. Hyaluronic Acid is normally found in the joints, the deeper layers of skin, in foetal skin and in the umbilical cord. Medical graded Hyaluronic Acid is usually helpful to diminish the incidence of post-operative adhesions, as a viscoelastic agent in intra-ocular surgery, also as a synovial replacement fluid; and is used to facilitate the healing and regeneration of surgical wounds. The unique properties of Hyaluronic Acid make it the ideal moisturizer. Hyaluronic Acid plays a crucial part in tissue hydration, lubrication and cellular behavior, and has the ability to hold more water than any other biological substance. Its incomparable hydrating properties produce augmented smoothness, softening and decreased wrinkles. Hyaluronic Acid has also proven to give excellent results in the reduction of dryness, itching and burning of the skin. It offers a perfect environment for the reproduction of new cells and healing following skin peels. Hyaluronic Acid is a major component of the extra-cellular matrix that circumscribes quickly dividing cells. It has been demonstrated to be an integral factor in the rapid and scarless wound healing seen in fetal and neonatal tissues. Moreover, the cellular actions precipitated by Hyaluronic Acid are integral to the apparently magical chemical processes of fetal development. It is well documented that fetal tissues have large amounts of Hyaluronic Acid and that decreasing Hyaluronic Acid quantities correlates with aging and wrinkling. Therefore any practical attempts to extend and recapture youth by revivifying damaged tissue should consider the inclusion of this molecule.
Vitamin O - Essential Oils - Nature's Answer To Oxygen Deficiency If there is any one BIG reason for you to use essential oils everyday, it can be summed up in one word...OXYGEN! Essential oils are loaded with it, at least 50 times more oxygen than what the plants give off from which they are derived. While essential oils may contain hundreds of different elements, three primary elements common to all oils are hydrogen, carbon and stabilized OXYGEN. So each time you inhale essential oils or apply them to your body, you are enriching your body with needed oxygen to purge toxins and fight off disease causing pathogens. This is why the use of essential oils on a daily basis can help you develop a superior immune system, and why people who use the oils (several times daily) seldom experience illness and disease. One of the incredible aspects of essential oils is their ability to penetrate and carry nutrients through the cell wall to the cell nucleous. Dr. Radwan Farag, Ph.D., head of the bio- chemistry department at Cairo University, is the man accredited for documenting the oxygenating and antioxidant activity essential oils afford. When the viscosity of blood is reduced, it's velosity increases. By increasing its velosity, our blood is able to deliver greater amounts of oxygen to tissues. When essential oils are introduced to the blood stream, they increase circulation, thereby increasing oxygenation. As the blood delivers nutrients and oxygen to the cells for feeding, it is the oxygenating molecules that penetrate and carry nutrients through the cell wall to the cell nucleous for feeding and oxidation. As the body grows oxygen deficient, individual cells begin to suffer. Without adequate oxygen, cells become nutritionally starved and become a garbage pit for waste and toxins, Deprived of nutrition, the cell protects itself by thickening its outer wall...making nutrient delivery even more difficult. This in turn causes cell deterioration, which can lead to cell mutation. It is in this state that the body becomes a host for disease causing pathogens. Due to their high oxygen content, essential oils are natures most effective catalyst and delivery agent for feeding cells. Rich in oxygen, they pass through the thickest cell walls with the greatest of ease (to maintain or begin a restorative process). This is just one of many ways in which essential oils help us. Because of their vast complexity and human individuality, modern science is just now beginning to realize we have only scratched the surface in understanding how essential oils work and interact within the human body.
White Tea was preceeded by green tea, known for being 200 times more potent than Vitamin E in its ability to destroy free radicals that can cause imperfections and premature aging of the skin. But research points to WHITE TEA -- as being three times more effective an antioxidant than green tea. Independent scientists at Case Western Reserve University in Cleveland have recently found that when a white-tea serum was applied to the skin before sun exposure, the polyphenols in the tea helped protect vital cells from damage during UV over-exposure. Without these, the skin is more prone to premature aging.
EFA-3 contains a unique ratio of Essential Fatty Acid extracts from Ultra-Pure Olive-derived Squalane from Italy along with Emu Oil to match that of the human skin.. Delivering all three Essential Fatty Acids, Omega-3, Omega-6, and Omega-9, directly into thirsty skin for immediate lipid replenishment. Because the body is not able to create Essential Fatty Acids on it’s own, topical supplementation is vital for soft, vibrant, younger-looking skin.
Retinol is the most effective form of vitamin A without a prescription. Retinol has demonstrated to give similar benefits to retin-A but without the irritation (and at a slower pace). Retinol increases cellular turnover which evens out tone and texture and helps skin to function better. Retinol is better than other forms of vitamin A as the molecular structure is smaller.
Anti-microbial Peptides repair disruption of the skin by acne inflammation, infection, sun damage, disease, lesions due to trauma, surgery, burns, accidents, or by chemical, dermabrasion or laser procedures used for skin renewal. AMP generates a signal to the natural immune system and initiates responses that may or may not be effective in a) preventing an impending invasion from surrounding microbes, b) inducing the production of antimicrobial peptides on the surface of the skin, and c) triggering the regeneration of new healthy cells to replace those damaged. Anti-microbial peptides (AMPs) protect the epithelial surfaces of all multicellular organisms from environmental microbes. Collectively AMPs exhibit activity against bacteria, fungi, viruses, and protozoa. These evolutionarily conserved peptides are usually positively charged and have both a hydrophobic and hydrophilic side that enables the molecule to be soluble in aqueous environments yet also enter lipid-rich membranes. Once in a target microbial membrane, the peptide kills target cells through diverse mechanisms. In man the best studied antimicrobial peptides expressed on skin and its appendages are the defensins, the cathelicidin LL37, and the recently described AMP, psoriasin. Most of the known AMPs are inducible. Topical agents such as the glycoconjugates stimulate local expression of epidermal AMPs and represent a novel class of skin care product. Decreased levels of these peptides have been noted for patients with atopic dermatitis and Kostmann's syndrome, a congenital neutropenia. In addition to important antimicrobial properties, growing evidence indicates that AMPs alter the host immune response through receptor-dependent interactions. AMPs have been shown to be important in such diverse functions as angiogenesis, wound healing, and chemotaxis. As our knowledge of AMP biology expands, the precise role and relevance of these peptides will be better elucidated.
Copper Peptides Glycosaminoglycans (GAGs) tightly binds divalent copper cations (Cu 2+) and form copper peptides, with reportedly have skin regeneration properties. The concentration of copper is notable, but copper peptides have been shown to be active in nanomolar amounts. Angiogenesis - the growth of new blood vessels - plays a central role in wound healing. Among many known growth factors, vascular endothelial growth factor (VEGF) is believed to be the most prevalent, efficacious, and long-term signal that is known to stimulate angiogenesis in wounds. Whereas a direct role of copper to facilitate angiogenesis has been evident two decades ago, the specific targets of copper action remained unclear. This report presents first evidence showing that inducible VEGF expression is sensitive to copper and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure. At physiologically relevant concentrations, copper sulfate induced VEGF expression in primary as well as transformed human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF expression. Topical copper sulfate accelerated closure of excisional murine dermal wound allowed to heal by secondary intention. Copper-sensitive pathways regulate key mediators of wound healing such as angiogenesis and extracellular matrix remodeling. Copper-based therapeutics represents a feasible approach to promote dermal wound healing. Certain types of copper peptide complexes possess both tissue protection and repair properties. Cu has protective and regenerative actions on several organ systems including skin, hair follicles, bone, gastric mucosa and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care products and after dermatological skin renewal procedures, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery. The greatest interest in copper peptides is in the area of reversing the effects of human aging and ultraviolet damage on human skin. During aging, skin becomes thinner and tends to accumulate various skin lesions and imperfections. The dermis and epidermis thin and the subcutaneous fat cells diminish in number. A number of studies have found that the application of copper peptide creams to the human skin is more effective in promoting collagen development than retinoic acid or vitamin C. It also increase s the thickness of the epidermis and dermis, increases skin elasticity, reduces wrinkles and removes skin imperfections such as blotchiness and sun damage marks.
Marine Soluble Collagen is collagen that has been processed to enable transdermal delivery. Marine collagen derived from salmon and marine source, naturally contains DMAE. DMAE, made popular by Dr. Nicolas Perricone, is a naturally occurring substance that facilitates the synthesis of a neurotransmitter acetylcholine, which help to maintain skins firmness and facial tone. DMAE also stimulates the synthesis of phosphatidylcholine, an important component of cell membranes. It’s soluble state, being fractionated for transdermal delivery, naturally encapsulates for skin absorption penetrates in the pores of the skin. This provides a significant soluble native collagen inflow, which has the following effects on the skin: It reduces wrinkles, is ultra hydrating, increases tone of the skin, helps healing, supports the growth of cells of the skin, procurez a bright and radiant complexion and it gives an ultra smooth and soft skin.
Emu Oil is derived from the Australian Emu bird, an oil that provides an unparalleled level of natural skin lipids that include omega 3's and essential fatty acids (Lipid-Peptides). Ingredients recommended by the world’s leading dermatologists for youthful skin. Emu Oil is highly moisturizing, a natural skin softener and has rejuvenating properties that have been shown to reduce the depth and length of fine lines and wrinkles. It is also non greasy and highly penetrating to the cellular level. Emu Oil has demonstrated to be the fastest and most penetrating oil into the skin, making it an excellent transdermal carrier for other therapeutic ingredients. It is an effective anti-inflammatory. It is also natural, non-toxic, non-comedogenic (does not clog pores), hypo-allergenic (non-irritating), and gentle for all skin types.
Vitamin K with Haloxyl has amazing anti-aging and anti-inflammatory properties that are wonderful for the eye area and has also been used topically to alleviate the discomfort and irritation following chemical peels and surgery (with the doctor’s permission). Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-3 have great firming and toning properties while the Chrysin, and Hydroxysuccinimide help lessen the under-eye circles and inflammation, and the Theophylline Sillinate is a super active caffeine derivative to draw excess fluid and reduce puffiness. This blend has green tea, cucumber, and chamomile to promote the healing of damaged skin and bruises as wekk as decrease the appearance of: redness of rosacea; dark under-eye circles; spider veins of the face; broken and distended blood vessels; and bruises (must be used two weeks prior to surgery and after surgery).
Vitamin E has been shown to have a wide variety of skin benefits. Many studies have shown that vitamin E can help decrease the effects of psoriasis, erythema, and may help in reducing the risk of skin cancer. Vitamin E has also been shown to significantly help in the reduction of scaring from wounds and has been shown to help reduce the appearance of stretch marks on the skin.
Bioflavonoids or Vitamin P may be active in preserving the structures of capillaries, have an antibacterial effect and promote circulation. They have been shown to aid the effectiveness of other vitamins when used in combination.
Aloe Vera has marvelous medicinal properties. Aloe Vera ‘healing’ comes from Growth Factors, Amino Acids, and minerals such as Zinc, as well as Polysaccharides. These biologically active agents synergize to give us the power of Aloe Vera. Epidermal and Fibroblast growth factors stimulate the Fibroblast directly for growth and repair. The cells as a result migrate within the wound in a proper manner to increase wound healing. Scientists have discovered over 150 nutritional ingredients in Aloe vera. There seems to be no single magic ingredient. They all work together in a synergistic way to create healing and health giving benefits. The ten main areas of chemical constituents of Aloe vera include: Glycoproteins, Gibberellin, Auxin, amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols. The amino acids in Aloe vera are the building blocks of protein and influence our brain function. Humans require 22 amino acids and the body will make all of them except for eight essential amino acids which our body gets from the food/drinks that we take in. Every one of the essential amino acids are available in Aloe vera and they include isoleucine, leucine, lysine, methionine, phenylalanine, threonine, valine,and tryptophan. Some of the other non-essential amino acids found in Aloe vera include alanine, arginine, asparagine, cysteine, glutamic acid, glycine, histidine, proline, serine, tyrosine, glutamine, and aspartic acid. Located in the sap of the leaves you will find twelve anthraquinones, a phenolic compound that has stimulating effects on the bowels and antibiotic properties. In small amounts the anthraquinones do not have a purgative effect. They help with absorption from the gastro intestinal tract and have anti-microbial and pain killing effects. Too many anthraquinones can produce abdominal pain and diarrhea. The most important anthraquinones are aloin and emodin. They are anti-bacterial, anti-viral, and analgesic. The anthraquinones in Aloe vera breakup residue, pus and lifeless cells, bring blood to the region and flush out material from the wounds and ulcers. Enzymes act as biochemical catalysts that break down the proteins we eat into amino acids. The enzymes turn the food we eat into fuel for every cell in our body, enabling the cells to function and work efficiently. “The main enzymes found in Aloe vera include Amylase (breaks down sugars and starches), Bradykinase (stimulates immune system, analgesic, anti-inflammatory), Catalase (prevents accumulation of water in the body), Cellulase (aids digestion - cellulose), Lipase (aids digestion - fats), Oxidase, Alkaline Phosphatase, Proteolytiase (hydrolyses proteins into their constituent elements), Creatine Phosphokinase (aids metabolism), and Carboxypeptidase.” The next thing we need to ask ourselves is what fuels the enzymes? The key is the vitamins and minerals we take in. For instance if we lack in zinc and/or Vitamin B6, our body will not be able to break down or use protein. Because of the healing properties of Aloe vera and its synergistic action, the body receives what it needs to work properly. Aloe vera, an anti-oxidant rich plant, contains vitamins such as A, C, and E plus the minerals, zinc, and selenium. Anti-oxidants help boost the immune system and combat free radicals in the body. It also contains Vitamins B1, B2, B3, B5, B6, and B12 along with choline, calcium (teeth and bone formation, muscle contractions and heart health), magnesium(strengthens teeth and bones, maintains healthy muscles and nervous system, activates enzymes), zinc (speeds up wound healing, mental quickness assists with healthy teeth, bones, skin, immune system, and digestive aid), manganese (activates enzymes, builds healthy bones, nerves and tissues), chromium (assists with protein metabolism and balancing of blood sugars), selenium which all influence our brain performance. Additional minerals found in Aloe vera include copper (important for red blood cells, skin and hair pigment), iron (involved in oxygen transportation and making of hemoglobin in red blood cells), potassium (helps with fluid balance), phosphorus (helps build bones and teeth, assists with metabolism and body pH), and sodium (regulates body liquids, helps with nerve and muscle performance, and helps deliver nutrients into body cells). Aloe vera also contains the trace minerals of rhodium and iridium used in cancer and tumor research experiments. Another component of Aloe vera consists of the lignins, a major structural material of cellulose content, that allows for penetrative properties. Aloe vera can soak into the skin up to seven layers deep. Lignins penetrate the toughened areas of the skin being beneficial for skin problems such as eczema and psoriasis. The next elements of Aloe vera we will discuss include monosaccharides and polysaccharides. Monosaccharides contain the simple sugars which include glucose. The polysaccharides are the more complex long-chain sugars involving glucose and mannose or the gluco-mannans. These sugars are ingested whole from the stomach. They do not get broken down like other sugars, and appear in the bloodstream in exactly the same form. This process is known as pinocytosis. Once in the blood stream, they exert their healing and immuno-regulating effect. Some of these polysaccharides are not absorbed but stick to certain cells lining the gut and form a barrier preventing absorption of unwanted material so helping to prevent a leaking gut syndrome. The sugars are also used in moisturizing preparations. One polysaccharide, acemannan, is known for its ability to restore and boost the immune system by stimulating the production of macrophages and improving the activity of T-Lymphocytes by up to 50 %. Acemannan produces immune agents such as interferon and interleukin which help to destroy viruses, bacteria, and tumor cells. Acemannan improves cellular metabolism by normalizing cellular function and regulating the flow of nutrients and wastes in and out of the cells. It knows how to destroy parasites and fungus. In some AIDS patients, it even protected the immune system from the toxic side effects of AZT. Carrington Laboratories in the United States have separated the acemannan from Aloe vera. The product is sold as “Carrisyn” and is being used for treatment of AIDS and Feline leukemia. Many sources stated that Aloe vera has mucopolysaccharides, nitrogen containing polysaccharides, found in animals and bacteria. A regulation and testing board for Aloe vera products known as the International Aloe Science Council concludes that some people are misinformed and confused on terminology. The Aloe has polysaccharides but not mucopolysaccharides. Aloe vera contains salicylic acid which is an aspirin-like compound with anti -inflammatory, analgesic, and anti-bacterial properties. It has anti-pyretic properties for reducing fevers. Other constituents of Aloe vera would include prostaglandins, tannins, magnesium lactate, resins, mannins, proteins such as lectins, monosulfonic acid and gibberlin. Another constituent of Aloe vera includes saponins. These are soapy substances from the gel that is capable of cleansing and having antiseptic properties. The saponins perform strongly as anti-microbial against bacteria, viruses, fungi, and yeasts. The plant sterols or phyto-steroids in Aloe vera include Cholesterol, Campesterol, Lupeol, and B (Beta sign) Sitosterol. The plant steroids have fatty acids in them that have antiseptic, analgesic, and anti-inflammatory properties.
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According to Dr. Leslie Baumann’s Cosmetic Dermatology, collagen production decreases by approximately 1 percent with each year of age after maturity (about age 21), leading to a loss in firmness and elasticity of skin. So what’s an age-conscious woman to do? Here are some options to stimulating collagen production.
1. Lasers
Two recently developed lasers are the Genesis and Medlite lasers, which have been reported in the Annals of Plastic Surgery to stimulate skin to make new collagen. Genesis and Medlite lasers are only administered by licensed dermatologists. Most women require three to six treatments, and the results should last three to five years. According to the March 2008 issue of Health magazine, Genesis and Medlite laser treatments are about $400 each. Check with a dermatologist near you for pricing and availability.
2. Facial Light Therapy
According to a recent study featured in the March 2008 issue of Allure magazine, LED phototherapy repairs sun damage and increases collagen and elastin production, although “lasers and peels have faster, more substantial results, but more side effects,” according to Seung Yoon Lee, a dermatologist at the National Medical Center in South Korea. With regards to LED therapy’s fewer side effects, Lee adds, “LED is safe for dark skin, unlike some lasers.”
According to Allure magazine, in the study, the researchers treated one side of 61 subjects’ faces with a light-emitting diode machine, while 15 others received a one-sided placebo treatment. Twelve weeks later, only the LED-targeted skin had a decrease in wrinkles (26-36 percent) and an increase in elasticity (14-19 percent). LED therapy seems to increase collagen and elastin production, although less significantly than lasers and peels.
3. Retinoid Treatments According to research by Fisher et. al cited by Dr. Baumann in Cosmetic Dermatology, retinoids are effective in preventing and treating the collagen loss caused by photodamage. UV exposure decreases collagen type I and collagen type III with 24 hours, but treatment of the skin with all-trans retinoic acid prevents the loss of these types of collagen synthesis. In addition, Fisher et. al demonstrated that application of tretinoin inhibits the induction of matrix metalloproteinase genes, which are in part responsible for collagen degradation. Your best option is to talk to your dermatologist about prescription retinoid treatments.
4. Glycolic Acid Peels
According to a 1998 study in Dermatological Surgery, glycolic acid treatments increase fibroblasts’ production of collagen in vivo (in hairless mice) and in vitro (in human skin fibroblast culture) better than either lactic acid or malic acid. However, if you’re deciding between prescription-strength retinoids and over-the-counter glycolic acid peels, you may want to choose the prescription retinoid cream. According to a randomized, placebo-controlled double-blind study, it was found that 0.05% all-trans-retinoic acid was more effective than 10% glycolic acid (a concentration found in at-home treatments) in treating signs of aging.
5. Topical Ascorbyl Palmitate Vitamin C Treatments
According to a review in the International Journal of Pharmaceutics, vitamin C triggers collagen production and thereby increasing skin firmness. Dr. Jeannette Graf also adds in Dr. Burgess’s Cosmetic Dermatology text, “Topical vitamin C increases levels of tissue inhibitors of collagen-degrading matrix metalloproteinases (MMP-1).” Vitamin C is particularly potent in conjunction with vitamin E; unfortunately, a 2008 Dermatology Therapy study cited in Best Life magazine found that very few products containing these vitamins remain effective. This is most likely because vitamin C becomes esterified and inactive upon exposure to light, air, and heat. Your best bet? Keep your vitamin C and E product tightly sealed and in a cool, dark place, or consider a stabilized form of vitamin C, although less research has been done on the effects of, say, 2% ascorbyl palmitate than 15% L-ascorbic acid.
6. Topical Peptide Treatments
Palmitoyl pentapeptide-3 has been shown to stimulate feedback regulation of new collagen synthesis and to result in an increased production of extracellular matrix proteins (collagen types I and II and fibronectin). For these reasons, palmitoyl pentapeptide-3 is increasingly popular in skin care products.
Palmitoyl oligopeptide is a second sequence of collagen-stimulating peptides. A 2007 study in Dermatologic Therapy suggests that palmitoyl oligopeptide significantly stimulates human skin collagen production in fibroblasts, which may slow the degradation of collagen over time.
7. Treatments with Collagen in the Ingredients
Collagen in skin care products acts as only a superior moisturizing ingredient. Topically applying collagen has never been shown to stimulate collagen synthesis or growth. This is because, according to Dr. Leslie Baumann in Cosmetic Dermatology, topically applied collagen is too large to fit through the stratum corneum (uppermost layer of the skin), as collagens have a molecular weight of 15000 to 50000 daltons, whereas only molecules of molecular weight 5000 or less can typically penetrate the skin.
8. Prevent Future Collagen Loss!
Don’t smoke. Wear sunscreen everyday and limit UV exposure. Eat - and topically apply - lots of anti-oxidants, which has been shown to be more effective than either method alone. Use retinoids or alpha hydroxy acids to increase cell turnover. And exercise - although the link between exercise and skin’s collagen production is only implied, always remember, what’s good for your health is good for your skin.
If you're like most people, you probably understand that collagen loss leads to aging skin and for that reason you need to use our skin care serum that contains collagen stimulating actives in order to combat its loss. It's important to understand that rubbing collagen into your skin is not going to prevent its loss. In order to combat the loss of collagen, you need to learn how to naturally produce collagen by using products that contain certain active ingredients. It might sound like a difficult task to naturally produce collagen protein. However, it is actually quite simple. A select few ingredients are known to stop the loss of collagen and elastin and stimulate their re-growth naturally. Here are the active ingredients that your skin needs in order to combat collagen loss.
1. Keratin
Hands down the best ingredient available for stimulating the collagen production in your skin. Keratin is a protein found throughout the body, which has an important structural role in the skin. The ability to convert natural keratin into a functional form that is readily-available to the skin is a recent breakthrough. This is a new exciting, cutting edge substance. Bioactive Keratin actually stimulates your own collagen to grow again. In fact, it is proven in clinical trials to stimulate not only the regrowth of collagen but also elastin, thereby promoting firmness and elasticity. In short, fewer wrinkles, and more youthful, healthier looking skin. It may help improve your skin's ability to retain its needed natural moisture.
Indeed, studies show a sustained 14% improvement in skin moisture retention over 18 days. Studies also show a sustained improvement in skin elasticity of 42% over 18 days. Bioactive Keratin penetrates your skin deeply and creates an invisible barrier that protects your skin and locks moisture in, which scientific studies show stimulates the production of new skin cells. Keratin stops the loss of collagen and stimulates its production. It also stimulates the production of elastin, another vital protein in the skin.
2. Active Manuka Honey
A special honey from New Zealand has unique healing properties. It has been used in skin care for centuries by the Maori people of New Zealand and it's easy to understand why. When used topically, Active Manuka Honey can restore and rejuvenate your skin. It supports the skin cell renewal process and assists in the formation of stronger collagen protein. As an added benefit, active manuka honey is rich in antioxidants and helps to reduce blemishes.
3. Avocado Oil If you want to know how to naturally produce collagen, you need to use face masks or creams that contain avocado oil. Avocado oil is deeply hydrating and highly compatible with the natural oils in your skin. Avocado oil is high in plant steroids, which help to reduce blemishes and age spots. It also helps to regenerate and rejuvenate skin damaged by free radicals. Avocado oil is important because it is scientifically proven to stimulate collagen production and it increases the proportion of soluble collagen in the dermis of your skin.
4. Wakame Sea Kelp
Wakame sea kelp extract is an exotic kelp native to the Japanese Sea, which raises the levels of hyaluronic acid in your skin by stopping the enzyme that is breaking it down. This increase will act to greatly smooth out many of the lines on your face. It works by blocking a harmful enzyme in your body called hyaluronidase. Hyaluronidase breaks down hyaluronic acid in your skin. You may think "well who cares." Well, you should because without hyaluronic acid, the elastin and collagen fibers lose their "glue," which leads to a loss of youthful appearance and dark eye circles. If you research this on Wikipedia, you will read, for example, "Hyaluronan is also a major component of skin, where it is involved in tissue repair."
5. CoEnzyme Q-10, Idebenone, Ubiquinone
In the 1970s and 1980s, researchers had been studying the potential of Coenzyme Q10 (CoQ10) to reduce free radical damage. A vitamin-like natural compound found in all aerobic organisms, it plays an important role in cellular energy production and is also an effective antioxidant. Trying to boost CoQ10's therapeutic effects, scientists synthesized and tested a variety of its chemical analogs and derivatives. Most of these derivatives were found ineffective or unsafe. However, one of the few exceptions was idebenone. It is closely related to CoQ10 in its structure. However, Idebenone is more effective than CoQ10 in protecting cells from the free radical damage resulting from reduced blood flow. The benefits of this ingredient include shielding skin from environmental damage, improving the appearance of fine lines and wrinkles, and reducing dryness and smoothing skin texture. If you look at the ingredient list for some of the better skin care products, you'll often see CoQ10 listed. CoQ10 is short for Coenzyme Q10, so you may also see it listed this way. CoQ10 is a vitamin like substance that is found in all of our body's cells and is very important for healthy skin. CoQ10 is a powerful anti-oxidant. A lot of skin damage and aging comes from free radicals wreaking havoc in our body's cells. CoQ10's anti-oxidant ability can counter these free radicals before damage occurs. Unfortunately, like many other vital substances, as we age, the amount of CoQ10 in our bodies becomes depleted. CoQ10 can penetrate deeply, it is extremely effective at ‘gobbling up’ free radicals in your skin. The result is a powerful anti-wrinkle effect, and can also promote collagen and elastin production as well. Together, these main active ingredients are some of the most powerful anti-aging skin care compounds available, and can significantly improve the look and feel of your skin. As you can see, it is possible to stop the loss of collagen protein in your skin, you can stimulate its re-growth. The result will be more youthful skin with improved elasticity, firmness, and tone. You will also notice a dramatic reduction in wrinkles and fine lines. Within days of using this serum, you will see a dramatic difference in the way your skin looks and feels by learning how to naturally produce collagen. So toss those "collagen" creams out and start using our CP Serum for a skin care product that will actually help you re-grow the collagen you have lost!
Idebenone is a Superceutical for The Next Level of Skin Rejuvenation and Free Radical Protection
What is it? Idebenone is the bioengineered cousin of the vital human antioxidant enzyme - CoEnzyme Q10 - but its 60% smaller (so it penetrates the skin) and up to 1000x more effective, simply put its "Super CoQ10".
How does it work? It targets aging at the cellular source - the mitochondria where it helps to revitalize the skin's cells by eliminating excess free radical formation that results from the way cells make energy - in effect it corrects the essence of cellular aging.
How is it unique? Unlike vitamin and botanical antioxidants, Idebenone is a respiratory chain antioxidant, a totally new kind of antioxidant, which can correct the signs of aging and also offers the highest protection against harmful environmental free radical stress with an Environmental Protection Factor of EPF 95, the highest rating of all antioxidants tested.
Why should I use it? Idebenone delivers a whole new level of skin rejuvenation that you cannot get from AHA, Vitamin A, Vitamin C or other cosmeceuticals because of its absolutely unique mode of action. If you have reached a plateau with your current skin care regimen and want the highest level of skin rejuvenation you can only get this from Idebenone the Superceutical.
Idebenone delivers multiple anti-aging benefits: • Helps prevent skin aging at its cellular source • Decreases the appearance of fine lines and wrinkles • Improves uneven skin tone and texture • Brightens the look of skin • Reduces the appearance of unwanted pigmentation • Offers maximum protection against environmental stress – EPF 95
6. Alpha Lipoic Acid
Lipoic acid is the strongest and longest lasting antioxidant. Lipoic Acid is both water-soluble and oil-soluble. Extremely powerful antioxidant that helps Vitamins C and E work more effectively in the skin. 400 times more powerful than Vitamin C as an antioxidant. Increases gluathione, the body's most important antioxidant. Powerful anti-inflammatory. It has anti-inflammatory qualities, which can be helpful in reducing the redness associated with rosacea, acne and sensitive skin types. It reduces the appearance of wrinkles, fine lines, dull skin, puffy eyes, and dark circles. This means it can fight free radicals in any part of a cell (intracellular) as well as the spaces in between the cells (intercellular). Lipoic acid increases the cell's metabolism, which allows the cell to take in more nutrients, eliminate more wastes, and replace more damaged components. It increases the free radical fighting properties of other antioxidants. Lipoic acid activates the transcription factor AP-1 that produces collagen-digesting enzymes that digest damaged collagen. Damaged collagen is responsible for wrinkles and scars so eliminating the damaged collagen can reverse aging. Lipoic acid is credited with reducing under-eye puffiness, sallow skin, enlarged pores, redness, lines, wrinkles, and acne scars.
Pepha-Tight
Pepha-Tight is a highly purified biotechnologically produced extract from the microalgae Nannochloropsis oculata combined with a well balanced fraction of polysaccharides. Pepha-Tight functions as a skin tightener which provides immediate tightening to the skin. It has been shown to protect human fibroblasts from oxidative stress, simultaneously increasing the formation of collagen-l thereby promoting a long term tightening effect through the strengthening of the skin's connective tissue. Pepha-Tight can be used for all skin tightening applications including lifting products, masks, decollete treatments, gels and serums.
Syn-Ake Tripeptide
Syn-Ake is formed from three amino acids joined by a peptide bond which forms the protein, or the synthetic version, of Viper venom. Syn®-ake has been developed as efficient smoothing and anti-wrinkle care particularly effective for expression lines by relaxing facial muscles. Addresses expression line, expression lines, fine lines, wrinkles, frown lines, worry lines, crows feet, laugh lines, pucker lines. The active compound derived from Heather Extract inhibits the action of the elastase enzyme which degrades the skins matrix. Documented claims shows that the formulation has the ability to reduce forehead expression line wrinkles by 52 per cent and crow's feet by 38 per cent in under one month.
Tripeptide mimics the activity of Waglerin 1, a protein found in the venom of the Temple Viper, Tropidolaemus wagleri 5% – a synthetic Tripeptide with excellent expression line anti-wrinkle properties. The peptide mimics the neuromuscular blocking properties of Waglerin 1, a polypeptide found in the venom of the snake Tropidolaemus wagleri. Reduce the appearance of wrinkles by 22% the 1st week. Tripeptide 5% Complex is the most effective alternative. This simple molecule, discovered in snake venom, has the effect of blocking neural signaling and muscular contraction.
Viper Serum is a natural and powerful alternative to BOTOX® and other cosmetic procedures, melting wrinkles and dramatically reducing fine lines within 20 minutes of application, and has a lasting effect. This reverses the signs of aging and can be used on the forehead, eye area, crow's feet, cheeks, laugh lines, lip area, and stretch marks on the body. In clinical studies, 100% of the respondents experienced a 50-90% reduction in the visible appearance of fine lines and wrinkles within 10 minutes of application. Our serum combines the tripeptide protein with a number of peptides and focused derivatives, including Antarticine, APT, MDI Complex, Aldenine, Pepha Tight, EUK 134 (an anti-oxidant) and a Hyaluronic Acid. Tripeptide mimics the activity of Waglerin 1, a protein found in the venom of the Temple Viper, Tropidolaemus wagleri 5% – a synthetic Tripeptide with excellent anti-wrinkle properties. The peptide mimics the neuromuscular blocking properties of Waglerin 1, a polypeptide found in the venom of the snake Tropidolaemus wagleri. Reduce the appearance of wrinkles by 22% the 1st week. Tripeptide 5% Complex is the most effective alternative. This simple molecule, discovered in snake venom, has the effect of blocking neural signaling and muscular contraction. Similarly, Botulinum Toxin (Active ingredient in BOTOX®) has the same mode of action when injected subcutaneously. Tripeptide is a smaller molecule than Botulinum Toxin, and is able to traverse the skin barrier effectively. The effects are unsurpassed when compared with any product on the market.
This high quality serum contains the best ingredient technology available in the market. This new active ingredient is safe, extensively tested, and approved for use in cosmetics. Why endure injections and costly medical procedures! Tripeptide is a revolutionary new compound discovered in snake venom, which relaxes facial muscle contractions. It works in exactly the same way that Botox Injections work. The difference is that Tripeptide works as a topical alternative, instead of injection. As well, it is reversible when usage is discontinued. There is no other product on the market, which is as efficacious. The discovery of this new Tripeptide enables consumers to have a Botox cosmetic alternative. Peptides are protein fragments. Tripeptide is a series of amino acids in sequence, which has bioactive response on muscular contractions. Viper Serum is a natural and powerful alternative to BOTOX® and other cosmetic procedures, melting wrinkles and dramatically reducing fine lines within 20 minutes of application, and has a lasting but not permanent effect. This reverses the signs of aging and can be used on the forehead, eye area, crow's feet, cheeks, laugh lines, lip area, and stretch marks on the body. In clinical studies, 100% of the respondents experienced a 50-90% reduction in the visible appearance of fine lines and wrinkles within 10 minutes of application.
Collagen and Collagen Synthesis
Many ingredients claim to help you naturally produce more collagen, but D (SS) Serum actually contains REAL ingredients that naturally stimulate the collagen production in your skin. It is very hard to find a product that contains all these collagen boosters because it is complex to properly manufacture, takes much longer to and is expensive to produce. The most powerful substance to help keep skin stay young, soft and vibrant is collagen. Collagen is what gives young skin its firmness. It is a natural protein that provides our skin with structural support. By replenishing the collagen levels in our skin, the aging process is drastically slowed down and existing wrinkles are quickly reversed or repaired. Collalgen helps skin become thicker, more youthful and elastic with hydrated skin so you begin looking younger within the first week. Fine lines and wrinkles begin to disappear and deeper wrinkles recede within three weeks, the face actually undergoes a visible change of youthful contour. Collagen is the glue that holds the body together. Collagen is the most abundant structural protein in the body 60% of the body is made up of connective tissue and collagen represents 80% of all connective tissue. 75% of the dermis consists of collagen and it accounts for 90% of dermal volume. From the age of approximately 25-35 years onwards the body loses collagen at a rate of 1.5% per annum. Collagen is not available from food. There are many face-lift programs and treatments on the market. But, these mostly work on the surface of the skin.